Publications

Metabolomics

  1. Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling. Ketterer S, Mitschke J, Ketscher A, Schlimpert M, Reichardt W, Baeuerle N, Hess ME, Metzger P, Boerries M, Peters C, Kammerer B, Brummer T, Steinberg F, Reinheckel T. Nat Commun. 2020 Oct 12;11(1):5133. doi: 10.1038/s41467-020-18935-2
  2. Enzymatic spiroketal formation via oxidative rearrangement of pentangular polyketides. Frensch B, Lechtenberg T, Kather M, Yunt Z, Betschart M, Kammerer B, Lüdeke S, Müller M, Piel J, Teufel R. Nat Commun. 2021 Mar 4;12(1):1431. doi: 10.1038/s41467-021-21432-9. PMID: 33664266
  3. Metabolic reprogramming of inner ear cell line HEI-OC1 after dexamethasone application. Kather M, Koitzsch S, Breit B, Plontke S, Kammerer B, Liebau A. Metabolomics. 2021 May 24;17(6):52. doi: 10.1007/s11306-021-01799-y. PMID: 34028607
  4. Metabolic and Lipidomic Assessment of Kidney Cells Exposed to Nephrotoxic Vancomycin Dosages. Lagies S, Pichler R, Vladimirov G, Gawron J, Bäzner F, Schreiner A, Kadena D, Plattner DA, Lienkamp SS, Kammerer B. Int J Mol Sci. 2021 Sep 18;22(18):10111. doi: 10.3390/ijms221810111. PMID: 34576273
  5. Pharmacokinetic study of the novel phosphocholine derivative 3-dibutylaminopropylphosphonic acid by LC-MS coupling. Kather MG, Zeller J, Plattner D, Breit B, Kreuzaler S, Krippner G, Peter K, Eisenhardt SU, Kammerer B. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Dec 1;1186:122998. doi: 10.1016/j.jchromb.2021.122998. Epub 2021 Nov 8.
  6. Metabolic Adaptation during nab-Paclitaxel Resistance in Pancreatic Cancer Cell Lines. Braun LM, Lagies S, Guenzle J, Fichtner-Feigl S, Wittel UA, Kammerer B. Cells. 2020 May 19;9(5):1251. doi: 10.3390/cells9051251
  7. Heat Stress-Induced Metabolic Remodeling in Saccharomyces cerevisiae. Pan D, Wiedemann N, Kammerer B. Metabolites. 2019 Nov 5;9(11):266. doi: 10.3390/metabo9110266.
  8. Biallelic variants in HPDL, encoding 4-hydroxyphenylpyruvate dioxygenase-like protein, lead to an infantile neurodegenerative condition. Ghosh SG, Lee S, Fabunan R, Chai G, Zaki MS, Abdel-Salam G, Sultan T, Ben-Omran T, Alvi JR, McEvoy-Venneri J, Stanley V, Patel A, Ross D, Ding J, Jain M, Pan D, Lübbert P, Kammerer B, Wiedemann N, Verhoeven-Duif NM, Jans JJ, Murphy D, Toosi MB, Ashrafzadeh F, Imannezhad S, Karimiani EG, Ibrahim K, Waters ER, Maroofian R, Gleeson JG. Genet Med. 2021 Mar;23(3):524-533. doi: 10.1038/s41436-020-01010-y. Epub 2020 Nov 14
  9. The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa. Brandel A, Aigal S, Lagies S, Schlimpert M, Meléndez AV, Xu M, Lehmann A, Hummel D, Fisch D, Madl J, Eierhoff T, Kammerer B, Römer W. Cell Mol Life Sci. 2021 Apr;78(7):3637-3656. doi: 10.1007/s00018-021-03766-1. Epub 2021 Feb 8. PMID: 33555391
  10. Christoph Bauer, Meret Quante, Willemijn B. Breunis, Carla Regina, Michaela Schneider, Geoffroy An-drieux , Oliver Gorka, Olaf Groß, Melanie Boerries, Bernd Kammerer*, Simone Hettmer*: : Lack of Electron Acceptors Contributes to Redox Stress and Growth Arrest in Asparagine-Starved Sarcoma Cells, Cancers (Basel)., accepted (Januar 2021) *shared corresponding authorship
  11. Britta Frensch, Thorsten Lechtenberg, Michel Kather, Zeynep Yunt, Martin Betschart, Bernd Kammerer, Steffen Lüdeke, Michael Müller, Jörn Piel, Robin Teufel:" Enzymatic spiroketal formation via oxidative rearrangement of pentangular polyketides", Nature Communications, accepted Januar 2021
  12. Danye Qiu, Miranda Wilson, Verena Eisenbeis, Robert Harmel, Esther Riemer, Thomas Haas, Christopher Wittwer, Nikolaus Jork, Chunfang Gu, Stephen Shears, Gabriel Schaaf, Bernd Kammerer, Dorothea Fiedler, Adolfo Saiardi, and Henning Jessen: "Analysis of Inositol Phosphate Metabolism by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry" Nature Communications 2020 (27;11(1):6035. doi: 10.1038/s41467-020-19928-x2020)
  13. Annette Brandel, Sahaja Aigal, Simon Lagies, Manuel Schlimpert, Anika Lehmann, Daniel Hummel, Daniel Fisch, Ana Valeria Meléndez, Josef Madl, Thorsten Eierhoff, Bernd Kammerer, Winfried Römer
    The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa
    Under revision Cell. Mol. Life Sci.(Oct 2020)
  14. Hirschfeld M, Ge I, Rücker G, Waldschmidt J, Mayer S, Jäger M, Voigt M, Kammerer B, Nöthling C, Berner K, Weiss D, Asberger J, Erbes T.: Mutually distinguishing microRNA signatures of breast, ovarian and endometrial cancers in vitro.
    Mol Med Rep. 2020 Nov;22(5):4048-4060. doi: 10.3892/mmr.2020.11466.
  15. Sanaz Taromi, Elke Firat, Alexander Simonis, Lukas Braun, Petya Apostolova, Mirjam Elze, Bernward Passlick, Alicia Heitzler, Simon Lagies, Anna Frey, Annette Schmitt-Graeff, Meike Burger, Katrin Schmittlutz, Silke Lassmann, Marie Follo, Sandra Duquesne, Dominik von Elverfeldt, Bernd Kammerer, Sven Diederichs, Justus Duyster, Markus Manz, Gabriele Niedermann, Robert Zeiser: AC133-specific CAR T cells combined with anti-PD1 and CD73 inhibition for metastatic small cell lung cancer; Submitted to Cancer Research (Aug. 2020).
  16. Shereen G. Ghosh, Sangmoon Lee, MD, , Rudy Fabunan, MS, Guoliang Chai, Maha S. Zaki, Ghada Abdel-Salam, Tipu Sultan, MBBS, Tawfeg Ben-Omran,, Javeria Raza Alvi,, Jennifer McEvoy-Venneri, Valentina Stanley, Aakash Patel, Danica Ross, Jeffrey Ding, Mohit Jain, Daqiang Pan, Philipp Lübbert, Bernd Kammerer, Nils Wiedemann, Nanda M. Verhoeven-Duif, Judith J. Jans, David Murphy, Mehran Beiraghi Toosi, Farah Ashrafzadeh Shima Imannezhad, Ehsan Ghayoor Karimiani, Khalid Ibrahim, Elizabeth R. Waters, Reza Maroofian, Joseph G. Gleeson: Biallelic Variants in HPDL, Encoding 4-Hydroxyphenylpyruvate Dioxygenase-Like Protein, lead to an Infantile Neurodegenerative Condition, Genetics in Medicine, 2020 Nov 14.
    doi: 10.1038/s41436-020-01010-y. Online ahead of print.
  17. Wilfried Reichardt, Natascha Baeuerle, Maria Hess, Patrick Metzger, Melanie Boerries, Christoph Peters, Bernd Kammerer, Tilman Brummer, Florian Steinberg, and Thomas Reinheckel: Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling Nature Communications 2020 Oct 12;11(1):5133. doi: 10.1038/s41467-020-18935-2
  18. Parigiani MA, Ketscher A, Timme S, Bronsert P, Schlimpert M, Kammerer B, Jacquel A, Chaintreuil P, Reinheckel T.: Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression. Cancers (Basel). 2020 Jul 22;12(8):E2004. doi: 10.3390/cancers12082004.
  19. Liang W, Yamahara K, Hernando-Erhard C, Lagies S, Wanner N, Liang H, Schell C, Kammerer B, Huber TB, Bork T.: A reciprocal regulation of Spermidine and Autophagy in Podocytes maintains the filtration barrier, Kidney Int. 2020 Jun 27:S0085-2538(20)30715-8. doi: 10.1016/j.kint.2020.06.016. Online ahead of print.
  20. Braun LM, Lagies S, Klar RFU, Hussung S, Fritsch RM, Kammerer B, Wittel UA: Metabolic Profiling of Early and Late Recurrent Pancreatic Ductal Adenocarcinoma Using Patient-Derived Organoid Cultures. Cancers (Basel). 2020 Jun 1;12(6):E144032492856
  21. Braun LM, Lagies S, Guenzle J, Fichtner-Feigl S, Wittel UA, Kammerer B: Metabolic Adaptation during nab-Paclitaxel Resistance in Pancreatic Cancer Cell Lines. Cells. 2020 May 19;9(5):1251.
  22. Lagies S, Schlimpert M, Neumann S, Wäldin A, Kammerer B, Borner C, Peintner L.: Cells grown in three-dimensional spheroids mirror in vivo metabolic response of epithelial cells. Commun Biol. 2020 May 19;3(1):246. 
  23. Liebau A, Schilp S, Mugridge K, Schön I, Kather M, Kammerer B, Tillein J, Braun S, Plontke SK. Long-Term in vivo Release Profile of Dexamethasone-Loaded Silicone Rods Implanted Into the Cochlea of Guinea Pigs. Front Neurol. 2020 Jan 22;10:1377.
  24. Pan D, Wiedemann N, Kammerer B.: Heat Stress-Induced Metabolic Remodeling in Saccharomyces cerevisiae. Metabolites. 2019 Nov 5;9(11). pii: E266.
  25. Lagies S, Pichler R, Bork T, Kaminski MM, Troendle K, Zimmermann S, Huber TB, Walz G, Lienkamp SS, Kammerer B.: Impact of Diabetic Stress Conditions on Renal Cell Metabolome. Cells. 2019 Sep 24;8(10). pii: E1141. doi: 10.3390/cells8101141.
  26. Shahinian JH, Rog-Zielinska EA, Schlimpert M, Mayer B, Tholen S, Kammerer B, Biniossek ML, Beyersdorf F, Schilling O, Siepe M.: Impact of Left Ventricular Assist Device Therapy on the Cardiac Proteome and Metabolome Composition in Ischemic Cardiomyopathy. Artif Organs. 2019 Sep 8. doi: 10.1111/aor.13566. [Epub ahead of print]

  27. Lagies S, Schlimpert M, Braun L, Kather M, Plagge J, Erbes T, Wittel U and Kammerer B: Unravelling altered RNA metabolism in pancreatic cancer cells by liquid-chromatography coupling to ion mobility mass spectrometry. Analytical and Bioanalytical Chemistry, 2019 , Sep; 411(24):6319-6328.

  28. Brinkkoetterm PT, Bork T, Salou S, Liang W, Özel C, Koehler S, Hagmann H, Schnyder S, Kuczkowski A, Ising C, Mizi A, Schermer B, Benzing T, Kretz O, Puelles VR, Lagies S, Schlimpert M, Kammerer B, Handschin, C, Schell C, and Huber TB: Anaerobic glycolysis maintains the glomerular filtration barrier independent of mitochondrial metabolism and dynamics. Cell reports  2019 Apr 30;27(5):1551-1566.e5

  29. Hirschfeld M, Ge IX; Ruecker G, Eismann J, Mayer S, Jaeger M, Voigt M, Kammerer B, Noethling C; Gitsch G, Berner K, Weiss D, Asberger J, Erbes T: Mutually distinguishing microRNA signatures of breast, ovarian and endometrial cancers in vitro. BMC Cancer, under revision (April 2019)

  30. Schlimpert M, Lagies S, Müller B, Budnyk V, Blanz KD, Walz G, Kammerer B: Metabolic Perturbations Caused by Depletion of Nephronophthisis Factor Anks6 in mIMCD3 cells. Metabolomics, submitted, minor revisions (November 2018)

  31. Schlimpert M, Lagies S, Budnyk V, Müller B, Walz G, Kammerer B. Metabolic Phenotyping of Anks3 Depletion in mIMCD-3 cells - a Putative Nephronophthisis Candidate. Scientific Reports 2018: 13;8(1):9022. doi: 10.1038/s41598-018-27389-y.

  32.  Lagies S, Pichler R, Kaminski MM, Schlimpert M, Walz G, Lienkamp SS, Kammerer B Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs). Scientific Reports 2018: 1;8(1):3878. doi: 10.1038/s41598-018-22073-7.

  33. Pan D, Lindau C, Lagies S, Wiedemann N, Kammerer B Metabolic profiling of isolated mitochondria and cytoplasm reveals compartment-specific metabolic responses. Metabolomics. 2018;14(5):59. doi: 10.1007/s11306-018-1352-x.

  34. Schönfeld CA, Huber R, Trittler R, Kammerer B, Käufer MC, Gründemann C Rosemary has immunosuppressant activity mediated through the STAT3 pathway, Complementary Therapies in Medicine 2018: Available online 11 March 2018, in press

  35. Kleiber A, Duan Q, Jansen K, Verena Junker L, Kammerer B, Rennenberg H, Ensminger I, Gessler A, Kreuzwieser J.Drought effects on root and needle terpenoid content of a coastal and an interior Douglas fir provenance.Tree Physiol. 2017 Dec 1;37(12):1648-1658. doi: 10.1093/treephys/tpx113.

  36. Junker LV, Kleiber A, Jansen K, Wildhagen H, Hess M, Kayler Z, Kammerer B, Schnitzler JP, Kreuzwieser J, Gessler A, Ensminger I.: „Variation in short-term and long-term responses of photosynthesis and isoprenoid-mediated photoprotection to soil water availability in four Douglas-fir provenances.”
    Scientific Reports (2017);7:40145.

  37. Pan D, Kather M, Willmann L, Schlimpert M, Bauer C, Lagies S, Schmidtkunz K, Eisenhardt SU, Jung M, Günther S, Kammerer B.: „Metabolic Response to XD14 Treatment in Human Breast Cancer Cell Line MCF-7.
    International Journal of Molecular Sciences. (2016) 24;17(10).

  38. Lucas Willmann, Manuel Schlimpert; Marc Hirschfeld; Thalia Erbes; Hans Neubauer; Elmar Stickeler; Bernd Kammerer: “Alterations of the exo- and endometabolite profiles in breast cancer cell lines: a mass spectrometry-based metabolomics approach”.
    Analytica Chimica Acta (2016) 21;925:34-42

  39. Thalia Erbes, Marc Hirschfeld, Silvia Waldeck, Gerta Rücker, Markus Jäger, Lucas Willmann, Bernd Kammerer, Sebastian Mayer, Gerald Gitsch, Elmar Stickeler: „Hyperthermia-driven aberrations of secreted microRNAs in breast cancer in vitro” International Journal of Hyperthermia.(2016) 32(6):630-42

  40. Du B, Jansen K, Kleiber A, Eiblmeier M, Kammerer B, Ensminger I, Gessler A, Rennenberg H, Kreuzwieser J.: „A coastal and an interior Douglas fir provenance exhibit different metabolic strategies to deal with drought stress.“
    Tree Physiology (2016), 36(2), 148-63

  41. Lucas Willmann; Manuel Schlimpert; Daqiang Pan; Christoph Bauer; Jens Trafkowski; Michael Rodamer; Ralf Falter; Bernd Kammerer: „Comprehensive two-dimensional liquid Chromatography in Metabolome Analysis“
    Journal of chromatography and separation techniques (2015), 6, (6)

  42. Willmann, Lucas; Erbes, Thalia; Halbach, Sebastian; Brummer, Tilman; Jaeger, Markus; Hirschfeld, Marc; Fehm, Tanja; Neubauer, Hans; Stickeler, Elmar; Kammerer, Bernd: “Exometabolom analysis of breast cancer cell lines: Metabolic signature” Scientific Reports (2015), 5, 13374.

  43. Willmann, Lucas; Schlimpert, Manuel; Halbach, Sebastian; Erbes, Thalia; Stickeler, Elmar; Kammerer, Bernd: „Metabolic profiling of breast cancer: Differences in central metabolism between subtypes of breast cancer cell lines” Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2015), 1000, 95-104.

  44. Willmann, Lucas; Erbes, Thalia; Krieger, Sonja; Trafkowski, Jens; Rodamer, Michael; Kammerer, Bernd: „Metabolome analysis via comprehensive two-dimensional liquid chromatography: identification of modified nucleosides from RNA metabolism” Analytical and Bioanalytical Chemistry (2015), 407(13), 3555-3566

  45. Koentges Christoph; Pfeil Katharina; Schnick Tilman; Wiese Sebastian; Dahlbock Rabea; Cimolai Maria C; Meyer-Steenbuck Maximilian; Cenkerova Katarina; Hoffmann Michael M; Jaeger Carsten; Kammerer Bernd; Lutz Hein, Christoph Bode, and Heiko Bugger.: “SIRT3 deficiency impairs mitochondrial and contractile function in the heart” Basic research in cardiology (2015), 110(4), 36.

  46. Jansen, Kirstin; Du, Baoguo; Kayler, Zachary; Siegwolf, Rolf; Ensminger, Ingo; Rennenberg, Heinz; Kammerer, Bernd; Jaeger, Carsten; Schaub, Marcus; Kreuzwieser, Juergen; Gessler, Arthur: „Douglas-fir seedlings exhibit metabolic responses to increased temperature and atmospheric drought “ PLoS One (2014), 9(12).

  47. Kiske C, Erxleben A, Lucas X, Willmann L, Klementz D, Günther S, Römer W, Kammerer B: “Metabolic Pathway Monitoring of Phenalinolactone Biosynthesis
    from Streptomyces sp. Tü6071 by LC-MS coupling”, Rapid Communications in Mass Spectrometry (2014), 28, 1459–1467.

  48. Jaeger C, Tellström V, Zurek G, König G, Eimer S, Kammerer B: “Metabolomic changes in Caenorhabditis elegans lifespan mutants as evident from GC–EI–MS and GC–APCI–TOF–MS profiling”, Metabolomics (2014), 10(5), 859-876.

  49. Rapp HM, Bacher S, Ahrens A, Rapp W, Kammerer B, Nienhaus GU, Bannwarth W: Attachment of Proteins to Surfaces by Fluorous-Fluorous Interactions Restoring their Structure and Activity, ChemPlusChem 2012, 77 (12): 1066-1070

  50. Teperino R, Amann S, Bayer M, McGee SL, Loipetzberger A, Connor T, Jaeger C, Kammerer B, Winter L, Wiche G, Dalgaard K, Selvaraj M, Gaster M, Lee-Young RS, Febbraio MA, Knauf C, Cani PD, Aberger F, Penninger JM, Pospisilik JA, Esterbauer H: Hedgehog Partial Agonism Drives Warburg-like Metabolism in Muscle and Brown Fat, Cell 2012, 151(2):414-26

  51. Hahn H, Salt AN, Biegner T, Kammerer B, Delabar U, Hartsock J, Plontke SK: Dexamethasone levels and base to apex concentration gradients in scala tympani perilymph following intracochlear delivery in the guinea pig, Otology & Neurotology 2012, 33(4):660-665.

  52. Zang Y, Kammerer B, Eisenkolb M, Lohr K, Kiefer H: Towards protein crystallization as a process step in downstream processing of therapeutic antibodies: screening and optimization at microbatch scale, PLoS One 2011, 6(9), e25282
  53. Härle J, Günther S, Lauinger B, Weber M, Kammerer B, Zechel DL, Luzhetskyy A, Bechthold A: Rational design of an aryl-C-glycoside catalyst from a natural product o-glycosyltransferase, Chem Biol 2011, 18(4): 520-530
  54. Siebenberg S, Kaysser L, Wemakor E, Heide L, Gust B, Kammerer B: Identification and structural elucidation of new caprazamycins from Streptomyces sp. MK730-62F2 by liquid chromatography/electrospray ionization tandem mass spectrometry, Rapid Commun Mass Spectrom 2011, 25:495-502
  55. Pena R, Offermann C, Simon J, Naumann PS, Gessler A, Holst J, Dannenmann M, Mayer H, Kogel-Knabner I, Rennenberg H, Polle A: Girdling affects ectomycorrhizal fungal (EMF) diversity and reveals functional differences in EMF community composition in a beech forest, Appl Environ Microbiol 2010, 76:1831-1841
  56. Kaysser L, Wemakor E, Siebenberg S, Salas JA, Sohng JK, Kammerer B, Gust B: Formation and attachment of the deoxysugar moiety and assembly of the gene cluster for caprazamycin biosynthesis, Appl Environ Microbiol 2010, 76:4008-4018
  57. Kaysser L, Siebenberg S, Kammerer B, Gust B: Analysis of the liposidomycin gene cluster leads to the identification of new caprazamycin derivatives, Chembiochem 2010, 11:191-196
  58. Henneges C, Laskov P, Darmawan E, Backhaus J, Kammerer B, Zell A: A factorization method for the classification of infrared spectra, BMC Bioinformatics 2010, 11:561
  59. Hehlgans S, Lange I, Eke I, Kammerer B, Cordes N: Human head and neck squamous cell carcinoma cell lines are differentially radiosensitised , Int J Radiat Biol, Epub 2010 Dec 10., 2011, 3:243-53
  60. Ruehr NK, Offermann CA, Gessler A, Winkler JB, Ferrio JP, Buchmann N, Barnard RL: Drought effects on allocation of recent carbon: from beech leaves to soil CO2 efflux, New Phytol 2009, 184:950-961
  61. Richter A, Wanek W, Werner RA, Ghashghaie J, Jaggi M, Gessler A, Brugnoli E, Hettmann E, Gottlicher SG, Salmon Y, Bathellier C, Kodama N, Nogues S, Soe A, Volders F, Sorgel K, Blochl A, Siegwolf RT, Buchmann N, Gleixner G: Preparation of starch and soluble sugars of plant material for the analysis of carbon isotope composition: a comparison of methods, Rapid Commun Mass Spectrom 2009, 23:2476-2488
  62. Rennenberg H, Dannenmann M, Gessler A, Kreuzwieser J, Simon J, Papen H: Nitrogen balance in forest soils: nutritional limitation of plants under climate change stresses, Plant Biol (Stuttg) 2009, 11 Suppl 1:4-23
  63. Pfautsch S, Gessler A, Adams MA, Rennenberg H: Using amino-nitrogen pools and fluxes to identify contributions of understory Acacia spp. to overstory Eucalyptus regnans and stand nitrogen uptake in temperate Australia, New Phytol 2009, 183:1097-1113
  64. Michaelis M, Rothweiler F, Klassert D, von Deimling A, Weber K, Fehse B, Kammerer B, Doerr HW, Cinatl J, Jr.: Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3, Cancer Res 2009, 69:416-421
  65. Kaysser L, Lutsch L, Siebenberg S, Wemakor E, Kammerer B, Gust B: Identification and manipulation of the caprazamycin gene cluster lead to new simplified liponucleoside antibiotics and give insights into the biosynthetic pathway, J Biol Chem 2009, 284:14987-14996
  66. Jaeger C, Gessler A, Biller S, Rennenberg H, Kreuzwieser J: Differences in C metabolism of ash species and provenances as a consequence of root oxygen deprivation by waterlogging, J Exp Bot 2009, 60:4335-4345
  67. Henneges C, Bullinger D, Fux R, Friese N, Seeger H, Neubauer H, Laufer S, Gleiter CH, Schwab M, Zell A, Kammerer B: Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection, BMC Cancer 2009, 9:104
  68. Gessler A, Tcherkez G, Karyanto O, Keitel C, Ferrio JP, Ghashghaie J, Kreuzwieser J, Farquhar GD: On the metabolic origin of the carbon isotope composition of CO2 evolved from darkened light-acclimated leaves in Ricinus communis, New Phytol 2009, 181:374-386
  69. Gessler A, Low M, Heerdt C, de Beeck MO, Schumacher J, Grams TE, Bahnweg G, Ceulemans R, Werner H, Matyssek R, Rennenberg H, Haberer K: Within-canopy and ozone fumigation effects on delta13C and Delta18O in adult beech (Fagus sylvatica) trees: relation to meteorological and gas exchange parameters, Tree Physiol 2009, 29:1349-1365
  70. Gessler A, Brandes E, Buchmann N, Helle G, Rennenberg H, Barnard RL: Tracing carbon and oxygen isotope signals from newly assimilated sugars in the leaves to the tree-ring archive, Plant Cell Environ 2009, 32:780-795
  71. Ferrio JP, Cuntz M, Offermann C, Siegwolf R, Saurer M, Gessler A: Effect of water availability on leaf water isotopic enrichment in beech seedlings shows limitations of current fractionation models, Plant Cell Environ 2009, 32:1285-1296
  72. Devaux M, Ghashghaie J, Bert D, Lambrot C, Gessler A, Bathellier C, Ogee J, Loustau D: Carbon stable isotope ratio of phloem sugars in mature pine trees throughout the growing season: comparison of two extraction methods, Rapid Commun Mass Spectrom 2009, 23:2511-2518
  73. Zurek G, Krebs I, Gotz S, Scheible H, Laufer S, Kammerer B, Albrecht W: A software solution automatically assigns formulae for construction of fragmentation pathways accelerating drug elucidation with ESI-TOF, LC GC Eur 2008, 31-33
  74. Wolpert M, Heide L, Kammerer B, Gust B: Assembly and heterologous expression of the coumermycin A1 gene cluster and production of new derivatives by genetic engineering, Chembiochem 2008, 9:603-612
  75. Plontke SK, Biegner T, Kammerer B, Delabar U, Salt AN: Dexamethasone concentration gradients along scala tympani after application to the round window membrane, Otol Neurotol 2008, 29:401-406
  76. Kodama N, Barnard RL, Salmon Y, Weston C, Ferrio JP, Holst J, Werner RA, Saurer M, Rennenberg H, Buchmann N, Gessler A: Temporal dynamics of the carbon isotope composition in a Pinus sylvestris stand: from newly assimilated organic carbon to respired carbon dioxide, Oecologia 2008, 156:737-750
  77. Heide L, Westrich L, Anderle C, Gust B, Kammerer B, Piel J: Use of a halogenase of hormaomycin biosynthesis for formation of new clorobiocin analogues with 5-chloropyrrole moieties, Chembiochem 2008, 9:1992-1999
  78. Gessler A, Tcherkez G, Peuke AD, Ghashghaie J, Farquhar GD: Experimental evidence for diel variations of the carbon isotope composition in leaf, stem and phloem sap organic matter in Ricinus communis, Plant Cell Environ 2008, 31:941-953
  79. Frickenschmidt A, Frohlich H, Bullinger D, Zell A, Laufer S, Gleiter CH, Liebich H, Kammerer B: Metabonomics in cancer diagnosis: mass spectrometry-based profiling of urinary nucleosides from breast cancer patients, Biomarkers 2008, 13:435-449
  80. Bullinger D, Fux R, Nicholson G, Plontke S, Belka C, Laufer S, Gleiter CH, Kammerer B: Identification of urinary modified nucleosides and ribosylated metabolites in humans via combined ESI-FTICR MS and ESI-IT MS analysis, J Am Soc Mass Spectrom 2008, 19:1500-1513
  81. Bullinger D, Frohlich H, Klaus F, Neubauer H, Frickenschmidt A, Henneges C, Zell A, Laufer S, Gleiter C, Liebich H, Kammerer B: Bioinformatical evaluation of modified nucleosides as biomedical markers in diagnosis of breast cancer, Anal Chim Acta 2008, 618:29-34
  82. Wolpert M, Gust B, Kammerer B, Heide L: Effects of deletions of mbtH-like genes on clorobiocin biosynthesis in Streptomyces coelicolor, Microbiology 2007, 153:1413-1423
  83. Vagin SI, Frickenschmidt A, Kammerer B, Hanack M: Reactivity of dehydrometallophthalocyanines and -porphyrazines, Chemistry 2007, 13:985-991
  84. Kammerer B, Scheible H, Zurek G, Godejohann M, Zeller KP, Gleiter CH, Albrecht W, Laufer S: In vitro metabolite identification of ML3403, a 4-pyridinylimidazole-type p38 MAP kinase inhibitor by LC-Qq-TOF-MS and LC-SPE-cryo-NMR/MS, Xenobiotica 2007, 37:280-297
  85. Roos L, vaan Daalen E, Lamers LPM, Roelofs JGM: How soil characteristics and water quality influence the biogeochemical response to flooding in riverine wetlands, Biogeochemistry 2007, 85:289–302
  86. Kammerer B, Scheible H, Albrecht W, Gleiter CH, Laufer S: Pharmacokinetics of ML3403 ({4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-( 1-phenylethyl)-amine), a 4-Pyridinylimidazole-type p38 mitogen-activated protein kinase inhibitor, Drug Metab Dispos 2007, 35:875-883
  87. Hauser DR, Scior T, Domeyer DM, Kammerer B, Laufer SA: Synthesis, biological testing, and binding mode prediction of 6,9-diarylpurin-8-ones as p38 MAP kinase inhibitors, J Med Chem 2007, 50:2060-2066
  88. Haberer K, Grebenc T, Alexou M, Gessler A, Kraigher H, Rennenberg H: Effects of long-term free-air ozone fumigation on delta15N and total N in Fagus sylvatica and associated mycorrhizal fungi, Plant Biol (Stuttg) 2007, 9:242-252
  89. Gessler A, Peuke AD, Keitel C, Farquhar GD: Oxygen isotope enrichment of organic matter in Ricinus communis during the diel course and as affected by assimilate transport, New Phytol 2007, 174:600-613
  90. Ehlting B, Dluzniewska P, Dietrich H, Selle A, Teuber M, Hansch R, Nehls U, Polle A, Schnitzler JP, Rennenberg H, Gessler A: Interaction of nitrogen nutrition and salinity in Grey poplar (Populus tremula x alba), Plant Cell Environ 2007, 30:796-811
  91. Dluzniewska P, Gessler A, Dietrich H, Schnitzler JP, Teuber M, Rennenberg H: Nitrogen uptake and metabolism in Populus x canescens as affected by salinity, New Phytol 2007, 173:279-293
  92. Bullinger D, Neubauer H, Fehm T, Laufer S, Gleiter CH, Kammerer B: Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling, BMC Biochem 2007, 8:25
  93. Brandes E, Wenninger J, Koeniger P, Schindler D, Rennenberg H, Leibundgut C, Mayer H, Gessler A: Assessing environmental and physiological controls over water relations in a Scots pine (Pinus sylvestris L.) stand through analyses of stable isotope composition of water and organic matter, Plant Cell Environ 2007, 30:113-127
  94. Barnard RL, Salmon Y, Kodama N, Sorgel K, Holst J, Rennenberg H, Gessler A, Buchmann N: Evaporative enrichment and time lags between delta18O of leaf water and organic pools in a pine stand, Plant Cell Environ 2007, 30:539-550
  95. Anderle C, Li SM, Kammerer B, Gust B, Heide L: New aminocoumarin antibiotics derived from 4-hydroxycinnamic acid are formed after heterologous expression of a modified clorobiocin biosynthetic gene cluster, J Antibiot (Tokyo) 2007, 60:504-510
  96. Anderle C, Hennig S, Kammerer B, Li SM, Wessjohann L, Gust B, Heide L: Improved mutasynthetic approaches for the production of modified aminocoumarin antibiotics, Chem Biol 2007, 14:955-967
  97. Anderle C, Alt S, Gulder T, Bringmann G, Kammerer B, Gust B, Heide L: Biosynthesis of clorobiocin: investigation of the transfer and methylation of the pyrrolyl-2-carboxyl moiety, Arch Microbiol 2007, 187:227-237
  98. Rennenberg H, Loreto F, Polle A, Brilli F, Fares S, Beniwal RS, Gessler A: Physiological responses of forest trees to heat and drought, Plant Biol (Stuttg) 2006, 8:556-571
  99. Peuke AD, Gessler A, Rennenberg H: The effect of drought on C and N stable isotopes in different fractions of leaves, stems and roots of sensitive and tolerant beech ecotypes, Plant Cell Environ 2006, 29:823-835
  100. Pelzing M, Zey T, Zurek G, Bullinger D, Frickenschmidt A, Laufer S, Kammerer B: Identification of urinary nucleosides by ESI-TOF-MS, LC GC N Am 2006, 14-16
  101. Nahm M, Radoglou K, Halyvopoulos G, Gessler A, Rennenberg H, Fotelli MN: Physiological performance of beech (Fagus sylvatica L.) at its southeastern distribution limit in Europe: seasonal changes in nitrogen, carbon and water balance, Plant Biol (Stuttg) 2006, 8:52-63
  102. Keitel C, Matzarakis A, Rennenberg H, Gessler A: Carbon isotopic composition and oxygen isotopic enrichment in phloem and total leaf organic matter of European beech (Fagus sylvatica L.) along a climate gradient, Plant Cell Environ 2006, 29:1492-1507
  103. Kahlich R, Gleiter CH, Laufer S, Kammerer B: Quantitative determination of piritramide in human plasma and urine by off- and on-line solid-phase extraction liquid chromatography coupled to tandem mass spectrometry, Rapid Commun Mass Spectrom 2006, 20:275-283
  104. Hansch R, Lang C, Riebeseel E, Lindigkeit R, Gessler A, Rennenberg H, Mendel RR: Plant sulfite oxidase as novel producer of H2O2: combination of enzyme catalysis with a subsequent non-enzymatic reaction step, J Biol Chem 2006, 281:6884-6888
  105. Hahn H, Kammerer B, DiMauro A, Salt AN, Plontke SK: Cochlear microdialysis for quantification of dexamethasone and fluorescein entry into scala tympani during round window administration, Hear Res 2006, 212:236-244
  106. Habermehl D, Kammerer B, Handrick R, Eldh T, Plasswilm L, Bamberg M, Belka C, Jendrossek V: The cytotoxic effectiveness of ukrainium is based on the effect of Chelidonium majus L.-alkaloids and is mediated over a mitochondrial apoptosis signal path, Strahlenther Onkol 2006, 182:91-91
  107. Habermehl D, Kammerer B, Handrick R, Eldh T, Gruber C, Cordes N, Daniel PT, Plasswilm L, Bamberg M, Belka C, Jendrossek V: Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway, BMC Cancer 2006, 6:14
  108. Haagen Y, Gluck K, Fay K, Kammerer B, Gust B, Heide L: A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042, Chembiochem 2006, 7:2016-2027
  109. Freitag A, Mendez C, Salas JA, Kammerer B, Li SM, Heide L: Metabolic engineering of the heterologous production of clorobiocin derivatives and elloramycin in Streptomyces coelicolor M512, Metab Eng 2006, 8:653-661
  110. Dluzniewska P, Gessler A, Kopriva S, Strnad M, Novak O, Dietrich H, Rennenberg H: Exogenous supply of glutamine and active cytokinin to the roots reduces NO3- uptake rates in poplar, Plant Cell Environ 2006, 29:1284-1297
  111. Vagin SI, Frickenschmidt A, Kammerer B, Hanack M: First generation and trapping of a dehydrometallophthalocyanine starting from triazole-functionalized zinc phthalocyanine, Chemistry 2005, 11:6568-6573
  112. Luft T, Li SM, Scheible H, Kammerer B, Heide L: Overexpression, purification and characterization of SimL, an amide synthetase involved in simocyclinone biosynthesis, Arch Microbiol 2005, 183:277-285
  113. Liebich HM, Muller-Hagedorn S, Klaus F, Meziane K, Kim KR, Frickenschmidt A, Kammerer B: Chromatographic, capillary electrophoretic and matrix-assisted laser desorption ionization time-of-flight mass spectrometry analysis of urinary modified nucleosides as tumor markers, J Chromatogr A 2005, 1071:271-275
  114. Liebich HM, Muller-Hagedorn S, Bacher M, Scheel-Walter HG, Lu X, Frickenschmidt A, Kammerer B, Kim KR, Gerard H: Age-dependence of urinary normal and modified nucleosides in childhood as determined by reversed-phase high-performance liquid chromatography, J Chromatogr B Analyt Technol Biomed Life Sci 2005, 814:275-283
  115. Kammerer B, Kahlich R, Ufer M, Schenkel A, Laufer S, Gleiter CH: Stereospecific pharmacokinetic characterisation of phenprocoumon metabolites, and mass-spectrometric identification of two novel metabolites in human plasma and liver microsomes, Anal Bioanal Chem 2005, 383:909-917
  116. Schollmeyer D, Kammerer B, Peifer C, Laufer S: 3(RS)-Bromo-3-(1(SR)-phenyl-propyl)-chroman-2,4-dione, Acta Chryst E 2005, 6(84): 868-869
  117. Kammerer B, Kahlich R, Ufer M, Laufer S, Gleiter CH: Achiral-chiral LC/LC-MS/MS coupling for determination of chiral discrimination effects in phenprocoumon metabolism, Anal Biochem 2005, 339:297-309
  118. Kammerer B, Kahlich R, Biegert C, Gleiter CH, Heide L: HPLC-MS/MS analysis of willow bark extracts contained in pharmaceutical preparations, Phytochem Anal 2005, 16:470-478
  119. Vagin S, Frickenschmidt A, Kammerer B, Hanack M: Synthesis and proporties of an unsymmetrical triazole-funcionalized (phthalocaninato)zinc complex, Eur JOC 2005, 15: 3271-3278
  120. Kammerer B, Frickenschmidt A, Muller CE, Laufer S, Gleiter CH, Liebich H: Mass spectrometric identification of modified urinary nucleosides used as potential biomedical markers by LC-ITMS coupling, Anal Bioanal Chem 2005, 382:1017-1026
  121. Kammerer B, Frickenschmidt A, Gleiter CH, Laufer S, Liebich H: MALDI-TOF MS analysis of urinary nucleosides, J Am Soc Mass Spectrom 2005, 16:940-947
  122. Endale A, Kammerer B, Gebre-Mariam T, Schmidt PC: Quantitative determination of the group of flavonoids and saponins from the extracts of the seeds of Glinus lotoides and tablet formulation thereof by high-performance liquid chromatography, J Chromatogr A 2005, 1083:32-41
  123. Bullinger D, Frickenschmidt A, Pelzing M, Zey T, Zurek G, Laufer S, Kammerer B: Identification of urinary nucleosides by ESI-TOF-MS, LC GC Eur 2005, 16-17
  124. Zyschka R, Brueckmann R, Kammerer B, Schreiber H: Wellne textiles finishing with vitamin E, Colourage 2005, 115-118
  125. Ufer M, Kammerer B, Kirchheiner J, Rane A, Svensson JO: Determination of phenprocoumon, warfarin and their monohydroxylated metabolites in human plasma and urine by liquid chromatography-mass spectrometry after solid-phase extraction, J Chromatogr B Analyt Technol Biomed Life Sci 2004, 809:217-226

  126. Scheible H, Laufer S, Unger A, Albrecht W, Gleiter CH, Kammerer B: In-vivo and in-vitro pharmacokinetics and biotransformation of ML 3403, a potent inhibitor of p38 MAP kinase. Int J Clin Pharmacol Ther 2004, 42: 625

  127. Ufer M, Kammerer B, Kahlich R, Kirchheiner J, Yasar U, Brockmoller J, Rane A: Genetic polymorphisms of cytochrome P450 2C9 causing reduced phenprocoumon (S)-7-hydroxylation in vitro and in vivo, Xenobiotica 2004, 34:847-859
  128. Kirchheiner J, Ufer M, Walter EC, Kammerer B, Kahlich R, Meisel C, Schwab M, Gleiter CH, Rane A, Roots I, Brockmoller J: Effects of CYP2C9 polymorphisms on the pharmacokinetics of R- and S-phenprocoumon in healthy volunteers, Pharmacogenetics 2004, 14:19-26
  129. Kahlich R, Gleiter CH, Laufer S, Kammerer B: Mass-spectrometric elucidation of piritramid metabolites by LC-ion-Trap-MSn technology. Int J Clin Pharmacol Ther 2004, 42:614
  130. Kammerer B, Kahlich R, Ufer M, Laufer S, Gleiter CH: Determination of (R)- and (S)-phenprocoumon in human plasma by enantioselective liquid chromatography/electrospray ionisation tandem mass spectrometry, Rapid Commun Mass Spectrom 2004, 18:458-464
  131. Kammerer B, Kahlich R, Laufer S, Li SM, Heide L, Gleiter CH: Mass spectrometric pathway monitoring of secondary metabolites: systematic analysis of culture extracts of Streptomyces species, Anal Biochem 2004, 335:17-29
  132. Vagin S, Hanack M, Kammerer B, Frickenschmidt A: Some reactions of magnesium arylporphyrazines: evidence for dehydroporphyrazine formation, Eur JOC 2004, 4245-4250

  133. Frickenschmidt A, Gräber I, Böttinger T, Laufer S, Gleiter CH, Liebich H, Kammerer B: Analysis of modified nucleosides in urine by MALDI-TOF-MS and MALDI-PSD. Int J Clin Pharmacol Ther 2004, 42:609

  134. Frickenschmidt A, Scheible H, Liebich H, Laufer S, Gleiter CH, Kammerer B: LC-MSn experiments with nucleosides and nucleic bases and identification of nucleosides in urine of breast cancer patients using LC-ESI-ion trap MS. Int J Clin Pharmacol Ther 2004, 42:608