Our collaborators

Signalling Factory

Collaboration projects (research lab and methods)

 

Labs listed in alphabetical order.  

 

Lab                 Dr. med. Peter Bronsert

                                https://www.uniklinik-freiburg.de/pathologie/forschung/ag-bronsert.html

Methods:               Cloning, Stable cell line generation (over-expression, immortalization)

Publication:          In preparation

 

Lab                 Prof. Dr. med. Dr. Judith Fischer

                                 https://www.uniklinik-freiburg.de/humangenetik/aktuelles.html

Methods:                Cloning, Protein expression and purification, Activity measurement

Publications:         A Monoallelic Two-Hit Mechanism in PLCD1 Explains the Genetic Pathogenesis of Hereditary Trichilemmal Cyst Formation. 
                                 Hörer S, Marrakchi S, Radner FPW, Zolles G, Heinz L, Eichmann TO, Has C, Salavei P, Mahfoudh N, Turki H, Zimmer AD, Fischer J.
                                 J Invest Dermatol. 2019 Oct;139(10):2154-2163.e5.

                                 Mutations in SULT2B1 Cause Autosomal-Recessive Congenital Ichthyosis in Humans.
                                 Heinz L, Kim GJ, Marrakchi S, Christiansen J, Turki H, Rauschendorf MA, Lathrop M, Hausser I, Zimmer AD, Fischer J.
                                 Am J Hum Genet. 2017 Jun 1;100(6):926-939. doi: 10.1016/j.ajhg.2017.05.007.

 

Lab                 Prof. Dr. Bodo Grimbacher

                                   https://www.uniklinik-freiburg.de/cci/forschung/bodo-grimbacher.html

Methods                 Establishing cell sorting method

 

Lab                 Prof. Dr. Andreas Hiltbrunner

                                 http://www.plantphotobiology.org/

Methods                 Establishing cell sorting method

 

Lab                 Prof. Dr. Carola Hunte

                                http://www.biochemie.uni-freiburg.de/de/ag/hunte

Methods                 Large scale cell culture (transfection), Stable cell line generation (over-expression and knock-out cell line), Confocal microscopy

Publication:          In progress

 

Lab                 Prof. Dr. Maja Köhn

                                https://www.bioss.uni-freiburg.de/groups/intergrated-signalling-studies/home/

Methods:               Confocal Microscopy

Publication:          Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A. Nat Commun. 2020 Jul 17;11(1):3583.

 

Lab                 Prof. Dr. Michael Köttgen

                                 http://www.nephrolab.org/groups/michael-koettgen

Methods:                 Cloning, Protein Expression and Purification, Establishing cell based library screening

 

Lab                 Prof. Dr. Thomas Laux

                                 https://laux.biologie.uni-freiburg.de/

Methods:                 Establishing cell sorting assay for plant cells

 

Lab                 PD Dr. Irina Nazarenko

                                 https://www.uniklinik-freiburg.de/iuk/forschungsgruppen/exosomen-und-tumorbiologie.html

Methods:                 Cloning, Stable cell line generation

Publications:           In process

 

Lab                 Dr. Remi Peyronnet

                                  undefinedhttps://www.herzzentrum.de/kliniken-fachbereiche/institut-fuer-experimentelle-kardiovaskulaere-medizin/team/remi-peyronnet-phd.html

Methods:                 Cloning, Stable cell line generation (knock-out and over-expression)

 

 

Lab                 Prof. Dr. Michael Reth

                              undefinedhttps://www.bioss.uni-freiburg.de/prof-dr-michael-reth

Methods:                 Cloning, Large scale protein expression and purification

 

 

Lab                 Prof. Dr. Winfried Römer

                                 https://www.bioss.uni-freiburg.de/groups/synthetic-biology-of-signalling-processes/syn-bio-signal-processes/

Methods:                 Protein expression, purification and refolding

Publications:           In preparation

 

Lab                 Dr. Günter Roth

                                 https://biocopy.ch/

Methods:                 Cloning, Kinetic measurements (Octet RED96 System)

Publication:            Comparison of different label-free imaging high-throughput biosensing systems for aptamer binding measurements using thrombin aptamers.
                                 Anal Biochem. 2019 Oct 15;583:113323. doi: 10.1016/j.ab.2019.05.012

 

Lab                 Prof. Dr. Oliver Schilling

                                 https://www.uniklinik-freiburg.de/pathologie/forschung/ag-schilling.html

Methods:                Cloning, Cell line generation (over-expression / knock-out cell line)

Publication:            Impact of DJ-1 and Helix 8 on the Proteome and Degradome of Neuron-Like Cells. Cells. 2021 Feb 16;10(2):404. doi: 10.3390/cells10020404.

 

Lab                 Prof. Dr. Prasad Shastri

                                 http://www.shastrilab.com

Methods:                Protein expression and purification, Stable cell line generation (over-expression / knock-out cell line), Cloning

Publication:            Disordered Conformation with Low Pii Helix in Phosphoproteins Orchestrates Biomimetic Apatite Formation.
                                Sarem M, Lüdeke S, Thomann R, Salavei P, Zou Z, Habraken W, Masic A, Shastri VP.
                                Adv Mater. 2017 Sep;29(35). doi: 10.1002/adma.201701629

 

Lab                 Dr. Maximilian Ulbrich

                                 http://www.ulbrichlab.com

Methods:                Cloning, Kinetic measurement (Octet RED96 System), Polarization measurement, Protein expression and purification, Stable cell line generation

Publications:          Designed membrane protein heterodimers and control of their affinity by binding domain and membrane linker properties.
                                  Lan C, Stulz A, Barthes N.P.F., Lauw S, Salavei P, Jung M, Heerklotzc H, and Ulbrich M.H.
                                  Nanoscale 2021 Dec 16;13(48):20692-20702, doi: 10.1039/d1nr06574b.

 

Lab                 Dr. med Stefan Vestring

                                 https://www.uniklinik-freiburg.de/psych/team/vestring.html

Methods:                qRT-PCR analysis, Western-Blot analysis

Publications:  

    

 

Lab                 Prof. Dr. Wilfried Weber

                                 https://www.bioss.uni-freiburg.de/groups/synthetic-biology/intro/

Methods:                 Large scale protein expression and purification

Publication:            Production of Phytochromes by High-Cell-Density E. coli Fermentation ACS Synth Biol. 2019 Oct 18;8(10):2442-2450.doi: 10.1021/acssynbio.9b00267.