Robotics Facility

Collaboration projects (research lab and methods)

 

Labs listed in alphabetical order.

 

Lab                 Prof. Dr. med. Dr. Judith Fischer

                                 https://www.uniklinik-freiburg.de/humangenetik/aktuelles.html

Methods:                Cloning, Protein expression and purification, Activity measurement

Publications:         A Monoallelic Two-Hit Mechanism in PLCD1 Explains the Genetic Pathogenesis of Hereditary Trichilemmal Cyst Formation. 
                                 Hörer S, Marrakchi S, Radner FPW, Zolles G, Heinz L, Eichmann TO, Has C, Salavei P, Mahfoudh N, Turki H, Zimmer AD, Fischer J.
                                 J Invest Dermatol. 2019 Oct;139(10):2154-2163.e5.

                                 Mutations in SULT2B1 Cause Autosomal-Recessive Congenital Ichthyosis in Humans.
                                 Heinz L, Kim GJ, Marrakchi S, Christiansen J, Turki H, Rauschendorf MA, Lathrop M, Hausser I, Zimmer AD, Fischer J.
                                 Am J Hum Genet. 2017 Jun 1;100(6):926-939. doi: 10.1016/j.ajhg.2017.05.007.

 

Lab                 Prof. Dr. Carola Hunte

                                http://www.biochemie.uni-freiburg.de/de/ag/hunte

Methods                 Establishing compound library screening method

Publication:           In progress

 

Lab                 PD Dr. K.P. Knobeloch

                                 https://www.uniklinik-freiburg.de/neuropathologie/forschung/molecular-genetics-pd-dr-kp-knobeloch.html

Methods:                 Establishing cell-based compound library screening assay

Publication:            In progress

 

Lab                 Prof. Dr. Michael Köttgen

                                 http://www.nephrolab.org/groups/michael-koettgen

Methods:                 Establishing cell based library screening assay

 

Lab                 Prof. Dr. Winfried Römer

                                 https://www.bioss.uni-freiburg.de/groups/synthetic-biology-of-signalling-processes/syn-bio-signal-processes/

Methods:                 Method development using Tecan Freedom Evo 200 robotic system I

Publications:           In process

 

Lab                 Dr. Günter Roth

                                 https://biocopy.ch/

Methods:                 Cloning, Kinetic measurements (Octet RED96 System)

Publication:            Comparison of different label-free imaging high-throughput biosensing systems for aptamer binding measurements using thrombin aptamers.
                                 Anal Biochem. 2019 Oct 15;583:113323. doi: 10.1016/j.ab.2019.05.012

 

Lab                 Prof. Dr. Wolfgang Schamel

                                 http://www.ulbrichlab.comhttps://www.bioss.uni-freiburg.de/groups/schamel-group/home/

Methods:                 Cell-based optogenetic screening method development using Tecan Freedom Evo 200 robotic system II

Publications:          In process

 

Lab                 Dr. Maximilian Ulbrich

                                 http://www.ulbrichlab.com

Methods:                Cloning, protein expression and purification, Kinetic measurement (Octet RED96 System), Polarization measurement

Publications:          Designed membrane protein heterodimers and control of their affinity by binding domain and membrane linker properties.
                                  Lan C, Stulz A, Barthes N.P.F., Lauw S, Salavei P, Jung M, Heerklotzc H, and Ulbrich M.H.
                                  Nanoscale 2021 Dec 16;13(48):20692-20702, doi: 10.1039/d1nr06574b.

 

Lab                 Dr. med Stefan Vestring

                                 https://www.uniklinik-freiburg.de/psych/team/vestring.html

Methods:                qRT-PCR analysis

Publications: