Publications

AG Warscheid

For further information on the impact of our proteomic-centered biological research on metabolic organelles and large signaling assemblies, please refer to the following selected publications:

Quantitative proteomics identifies zinc-based redox switches for global translation modulation by mitochondrially produced reactive oxygen species. Topf U, Suppanz I, Samluk L, Wrobel L, Böser A, Sakowska P, Knapp B, Pietrzyk MK, Chacinska A*, Warscheid B* (2018), Nat Commun 9:324.

Definition of a high confidence mitochondrial proteome at quantitative scale. Morgenstern M, Stiller SB, Lübbert P, Peikert CD, Dannenmeier S, Drepper F, Weill U, Höß P, Feuerstein R, Gebert M, Bohnert M, van der Laan M, Schuldiner M, Schütze C, Oeljeklaus S, Pfanner N, Wiedemann N*, Warscheid B* (2017), Cell Rep 9:2836-2852.

Charting organellar importomes by quantitative mass spectrometry. Peikert CD, Mani J, Morgenstern M, Sandro K, Knapp B, Wenger C, Harsman A, Oeljeklaus S, Schneider A*, Warscheid B* (2017). Nat Commun 8, 15272.

Myofibrillar Z-discs are a protein phosphorylation hot spot with protein kinase C (PKCalpha) modulating protein dynamics. Reimann L, Wiese H, Leber Y, Schwäble AN, Fricke A, Rohland A, Knapp B, Peikert CD, Drepper F, van der Ven PFM, Radziwill G, Fürst DO, Warscheid, B (2016). Mol Cell Proteomics 16, 346-67.

Pex17p-dependent assembly of Pex14p/Dyn2p-subcomplexes of the peroxisomal protein import machinery. Chan A, Schummer A, Fischer S, Bender J, Drepper F, Oeljeklaus S, Kunau WH, Girzalsky W, Warscheid B*, Erdmann R* (2016), Eur J Cell Biol, 95, 585-597.

The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins. Harsman A, Oeljeklaus S, Wenger C, Huot JL, Warscheid B*, Schneider A* (2016). Nat Commun 7, 13707.

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol. Wrobel L, Topf U, Bragoszewski P, Wiese S, Sztolsztener ME, Oeljeklaus S, Varabyova A, Lirski M, Chroscicki P, Mroczek S, Januszewicz E, Dziembowski A, Koblowska M, Warscheid B*, Chacinska A* (2015). Nature 524, 485-8.

Functional proteomics identifies acinus L as a direct insulin- and amino acid-dependent mammalian target of rapamycin complex 1 (mTORC1) substrate. Schwarz JJ, Wiese H, Tölle RC, Zarei M, Dengjel J, Warscheid B*, Thedieck K* (2015). Mol Cell Proteomics 14, 2042-55.

Structural basis of calcium-calmodulin regulation of hemidesmosome disassembly. Song JG, Kostan J, Drepper F, Knapp B, Wiche G, Gregor M, Warscheid B, Djinovic-Carugo K (2015). Structure 23,558-570.

The membrane proteome of sensory cilia to the depth of olfactory receptors. Kuhlmann K, Tschapek A, Wiese H, Eisenacher M, Meyer HE, Hatt H, Oeljeklaus S, Warscheid B (2014). Mol Cell Proteomics 13, 1828-1843.

Mitochondrial outer membrane proteome of Trypanosoma brucei reveals novel factors required to maintain mitochondrial morphology. Niemann M, Wiese S, Mani J, Chanfon A, Jackson C, Meisinger C, Warscheid B*, Schneider A* (2013). Mol Cell Proteomics 12, 515-528.

MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation. Mick DU, Dennerlein S, Wiese H, Reinhold R, Pacheau-Grau D, Lorenzi I, Sasarman F, Weraarpachai W, Shoubridge EA, Warscheid B, Rehling P (2012). Cell 151, 1528-41.

Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes. Gebert M, Schrempp SG, Mehnert CS, Heißwolf AK, Oeljeklaus S, Ieva R, Bohnert M, von der Malsburg K, Wiese S, Kleinschroth T, Hunte C, Meyer HE, Haferkamp I, Guiard B, Warscheid B, Pfanner N, van der Laan M (2012). J Cell Biol 197, 595-604.

Identification of core components and transient interactors of the peroxisomal importomer by dual-track SILAC analysis. Oeljeklaus S, Reinartz BS, Wolf J, Wiese S, Tonillo J, Podwojski K, Kuhlmann K, Stephan C, Meyer HE, Schliebs W, Brocard C, Erdmann R, Warscheid B (2012). J Proteome Res 11, 2567-2580.